This talk was given at a local TEDx event, produced independently of the TED Conferences. Recent discoveries (many in my lab) on the links between type 2 diabetes and Alzheimer’s disease; translation of that lab work into real-life advice and consequences.
My work examines the role of metabolic processes in regulating brain function, and specifically in regulating memory processing. We use a variety of animal models to examine the behavioral and neurochemical impact of modulations including diet-induced insulin resistance, beta-amyloid, insulin, and recurrent hypoglycemia.
Key discoveries have included:
Drainage of glucose from the brain extracellular fluid at times of high cognitive demand, showing that glucose demand can exceed supply and be limiting for cognitive performance.
Altered brain glucose transport and diffusion in the aged brain.
A key role for insulin in hippocampal cognitive and metabolic processes; conversely, the impact of insulin resistance on hippocampal function.
The cognitive, metabolic and neural impact of recurrent hypoglycemia (RH), a key side-effect of insulin therapy that limits achievement of target blood glucose levels in patients with diabetes. Recently, the mechanistic links between RH and subsequent weight gain.
Mechanistic links between beta-amyloid and both (i) hippocampal metabolism and (ii) central insulin signalling.
A central role for GluT4 in hippocampal cognitive processes.
To date I have roughly 50 peer-reviewed journal papers with ~2500 citations, at an h-index of 26; my work has been funded by the NIH, ADA, JDRF, Alzheimer’s Association and several state and private grants. In addition, my lab has won awards for excellence in student research every year during my time at U.Albany, and I have several teaching and mentoring awards.
From a patient or layperson’s point of view, my work shows that lifestyle elements – such as lack of exercise, caffeine intake, drinking red wine, or overeating – have direct and measureable impact on brain function, diseases such as Alzheimer’s disease, and risk of death. We can make specific recommendations for change, and show at the molecular level how choices made every day about diet – and even about things like doing a crossword instead of watching TV – affect your brain’s function.
About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
Dr. Buhler served as the team sports chiropractor for the Utah Jazz Basketball Team for 26 years. During his tenure with the Utah Jazz, he was instrumental in creating the lowest «Player Missed Games due to Injury Rate» of any team in the NBA for 26 years. He has treated world class, elite athletes as well as the general public who testify of his special ability to assist them in improved performance and wellness. Traveling with five patients to the 2010 Vancouver winter games, two of them won medals, one a Bronze and the other a Gold. Dr. Buhler is also a provider for the US Ski Team.
Dr. Buhler received his Doctor of Chiropractic degree in 1978 from Western States Chiropractic College in Portland Oregon. After graduation Dr. Buhler completed a Post Doctoral Fellowship at the University of Utah school of Medicine in the physiology department focusing on the conditions of motor physiology. In addition to being on the medical team of the Jazz he has had a successful practice in Utah for 35 years. Dr. Buhlers patients travel from all over the world to experience the healing benefits of this transformational work.
He enjoys spending time with his six daughters, skiing and riding horses. His passion is assisting young athletes in reaching their full potential and helping their dreams come true.
In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
Алексей Ли задается вопросом, уехать ли за границу и обеспечить своим детям лучшую жизнь или остаться в Казахстане и строить эту лучшую жизнь здесь. Но как это сделать? Как сформировать среду, которая позволит появиться и развивать инновационные проекты казахстанским Илонам Маскам?
Программист, основатель веб-студии «Глатис»
This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at ted.com/tedx
Are you ready to talk about relationships? Alexandra Redcay is the executive director to Serise, Inc. She can be found at Seriseinc.com. Alexandra has over 18 years of direct practice, management, and training experience working in mental health, substance abuse, child welfare, juvenile justice, and education systems. She is an expert consultant in establishing healthy relationships.
In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
This talk was given at a local TEDx event, produced independently of the TED Conferences. Что, если все книги по тайм-менеджменту были написаны лишь для рациональной половины человечества? Что делать, если вы принадлежите ко второй половине? Если все ваши усилия по планированию приводят к нулевым результатам? Как избавится от чувства вины при виде бесконечного списка отложенных дел? И можно ли выжить во всем этом хаосе?
Alexander Sorokoumov — management consultant, strategy sessions moderator, the author of books ‘Success strategies in the transition period. Business coaching’ and ‘Business transformation’, co-founder flytask.pro
About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
Иосиф Бродский и Сергей Довлатов… Герои питерских коммуналок, гордые одиночки, странники, культовые фигуры своего времени. Как пересекались их судьбы? Что происходило с ними в Ленинграде и в США?
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